NBIC14	Microbial Pathogenesis, 15 ECTS-points /MIKROBIELL PATOGENES/ Advancement level: C
	Aim: The shall should acquire knowledge about the role of microorganisms (virus, bacteria) in the human ecosystem. The course focuses on microbial pathogenesis and how microorganisms interact with the host defense. Prerequisites: Basic program of biology with fullfilled "threshold"-demands (passed 50p with a min of 25p theory). Course organization: Lectures and literature studies. Laboratory projects are included to exemplify the theory and their results are presented and discussed at seminars. The course also include presentation of scientific literature. The course is given by IFM/Biology together with Institute II/Department for Microbiology, Faculty of Health Sciences and IFM/Applied Physics. Course content: Studies of microbial pathogenesis and virulence mechanisms at the molecular and cellular level for bacteria and virus. Virulence gene regulation. Microbial adhesion. Artificial surfaces and protein adsorbtion. Foreign body infection. Modes of action of antimicrobial agents. Host responses, including inflammation and immune modulation ot the infections processes. Course literature: Abigal, A Salyers and Dixie, D Whitt: Bacterial Pathogenesis. A Molecular Approach. ASM Press. 1994. B Axelsson: Introduktion till Immunologi. (Manual). 1994. Laboratory Manual from the department. Complement literatur: Madigan et al: Brock Biology of the microorganisms. Prentice-Hall. 1997.
TEN2	Written examination
LAB2	Laboratory course
PROB	Presentation of literature studies.

Course language is swedish.