| TFYA32 |
Industrial Biotechnology, 6 ECTS credits.
/Industriell bioteknik/
For:
KeBi
TB
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Prel. scheduled
hours: 56
Rec. self-study hours: 104
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Area of Education: Science/Technology
Main field of studies: Engineering Biology
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Advancement level
(G1, G2, A): A
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Aim:
Fundamental understanding of industrial biotechnology with focus on products such as drugs, food, chemicals, renewable energy sources and instruments and process equipment. Understanding of metabolic and cell biological processes from engineering perspectives.
After the course the student shall be able to:
- Describe the fundamental biological and engineering principles for production of proteins, metabolites and cells and devices and apparatuses.
- Understand the principles for design of key unit operations and other functional operations such as bioreactor cultivation and chromatographic separation of bioproducts and analytical instruments.
- Carry out engineering computations of bioprocesses based on physical, chemical and biological fundamentals using basic mathematical equations and models.
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Prerequisites: (valid for students admitted to programmes within which the course is offered)
Basic biology, chemistry and mathematics as in the TB/KB curricula of 1-3 years, or equivalent. Knowledge in simulations of differential equations.
Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshhold requirements for progression within the programme, or corresponding.
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Supplementary courses:
Biotechnical production systems, Design project for bioprocesses and production systems, Biotechnology manufacturing technique, Pharmaceutical Development, Quality management.
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Organisation:
Lectures and seminars. Simulation exercises.
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Course contents:
The lectures cover fundamentals about industrial production using bioprocesses. This includes methods for cultivation in bioreactors and recovery of bioproducts using separation methods. Engineering modelling methods are used to calculate key process parameters. Content of lectures: Biochemistry and physiology of cell growth and metabolism. "The Cell Factory" concept. Bioreactor design for batch, fed-batch and chemostat. Purification and separation processes. Using dynamic models and differential equations based on balances and microbial kinetics. Design of unit operations for cultivation and bioseparation. Typical industrial bioprocesses are illuminated (e.g. production of antibiotics, biogas, industrial enzymes, therapeutic proteins, vaccines, mammalian cells, stem cells and environmental applications).
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Course literature:
Mandenius CF, Industriell bioteknik, Tryckakademin, Linköping
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Examination: |
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Written examination
Written reports
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4,5 ECTS
1,5 ECTS
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A written examination tests the student's ability to solve process engineering problems and ability to describe fundamental concepts in industrial biotechnology. Laboratory exercise reports examine the understanding of biological, physical and chemical effects and transformations using simulations and other calculation methods. |
Course language is Swedish.
Department offering the course: IFM.
Director of Studies: Magnus Boman
Examiner: Carl-Fredrik Mandenius
Course Syllabus in Swedish
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