| TVCB02 |
Gene Technology and Molecular Genetics, 6 ECTS credits.
/Genteknik och molekylärgenetik/
For:
TB
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Prel. scheduled
hours: 52
Rec. self-study hours: 108
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Area of Education: Science
Main field of studies: Engineering Biology
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Advancement level
(G1, G2, A): G2
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Aim:
The course intends to provide theoretical knowledge in basic genetics and molecular genetic mechanisms. Furthermore, the course should illuminate theoretical and practical knowledge in gene technology and its application in biomedicine. By the end of the course the student will be able to:
- Integrate knowledge on how genetic information is inherited, expressed and regulated.
- Understand and explain how genetic variation originates, and affects traits and development of disease in individuals.
- Understand the theoretical background as well as perform and analyse the results of basic molecular genetic methods.
- Understand the theoretical background of more advanced gene technologies for analysis of expression and variation in the genome, mapping and cloning of genes.
- Identify relevant analytical methods for application on a specific biomedical problem.
- Independently identify a genetic topic, as a foundation for searching scientific information, which will be structured, evaluated and presented in written and oral form.
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Prerequisites: (valid for students admitted to programmes within which the course is offered)
Biochemistry and Cell Biology
Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshhold requirements for progression within the programme, or corresponding.
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Supplementary courses:
Genome Analysis
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Organisation:
The course consists of lectures, seminars and laboratory work.
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Course contents:
- Genetic and molecular genetic principles for inheritance, meiosis, mitosis, recombination and linkage analysis.
- Mutations, polymorphisms, DNA repair and control of gene expression in eukaryotic cells.
- Medical genetics and application of gene technologies within biomedicine, disease diagnostics, prenatal diagnostics and genetic counselling as well as applications in forensic science.
- Basic gene technologies: restriction enzymes and RFLP, separation, labelling and hybridisation of nucleic acids, PCR-based techniques and DNA sequencing. Utilising of bioinformatic tools and databases for molecular genetic studies.
- Advanced gene technologies: mutation- and expression analysis, isolation and mapping of genes, animal models for functional studies, cytogenetics.
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Course literature:
Strachan, Tom & Read, Andrew P.: Human Molecular Genetics, BIOS Scientific Publishers Ltd, Oxford, UK, 3rd ed, 2003.
Alberts B. et al: Molecular Biology of the Cell, Garland Publ. Co., New York and London, 4th ed, 2002.
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Examination: |
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Written examination
Labratory work
Written examination
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3 ECTS
1,5 ECTS
1,5 ECTS
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Course language is Swedish.
Department offering the course: IKE.
Director of Studies: Kajsa Holmgren Peterson
Examiner: Peter Söderkvist
Course Syllabus in Swedish
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