| TBMT37 |
Models in System Biology, 2 ECTS credits.
/Systembiologisk modellering/
For:
KeBi
|
| |
Prel. scheduled
hours: 18
Rec. self-study hours: 35
|
| |
Area of Education: Engineering
Main field of studies: Biotechnology
|
| |
Advancement level
(G1, G2, A): G2
|
|
Aim:
This course will provide experience in mathematical modeling of biological systems. After completing this course, the participant shall be able to:
- explain why mathematical modeling is a tool in biological experimentation; explain some of the common mistakes
- construct a mathematical model of a class of biological systems
- analyzing, structuring and simulating mathematical models based on differential equations
- use methods for structured modeling in systems biology
- adapt mathematical models to measured data
- validate mathematical models to measured data; basic statistical tests
- use modern computerized tools for mathematical modeling in systems biology
- apply and integrate this with knowledge from previous courses
|
|
Prerequisites: (valid for students admitted to programmes within which the course is offered)
Basics courses in Chemistry, Biology and Mathematics
Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshhold requirements for progression within the programme, or corresponding.
|
|
Organisation:
The course consists of lectures and a large laboratory assignment and voluntary pre-assignments. The course is examined by two minor tests together with oral discussions of the laboratory work.
The course runs for the first three weeks during the spring semester.
|
|
Course contents:
Lectures, laboratory work covers:
- Systems biology: what it is, methods, issues and opportunities.
- Mathematical modeling. Types of models and their properties.
- Software for mathematical modeling and simulation in systems biology.
- System Identification: adaptation of mathematical models to experimental data.
- Validation and use of mathematical models. Troubleshooting and uncertainty analysis
|
|
Course literature:
Gunnarâ?Ts Crash Course in Systems Biology. Online-lectures.
|
|
Examination: |
|
Tests
|
2 ECTS
|
| |
|
Grades are given as â?TFailâ?T or *Passâ?T.
|
Course language is English.
Department offering the course: IMT.
Director of Studies: Marcus Larsson
Examiner: Gunnar Cedersund
Course Syllabus in Swedish
|