| TFYA62 |
Introduction to Biosensor Technology, 6 ECTS credits.
/Introduktion till biosensorteknik/
For:
I
Ii
MED
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Prel. scheduled
hours: 80
Rec. self-study hours: 80
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Area of Education: Science
Main field of studies: Physics, Applied Physics, Biomedical Engineering
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Advancement level
(G1, G2, A): G2
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Aim:
The purpose of the course is to provide a broad introduction to biosensor technology including:
- Working principle of the biosensors,
- Biosensors classification,
- Use of biological macromolecules as sensing elements,
- Presenting how engineering and biology can be used to perform diagnosis.
After finishing the course the student should be able to:
- Describe the working principles of biosensors,
- Explain the nature and mechanism of the biorecognition event,
- Describe and explain the main transduction techniques used in biosensor technology,
- Evaluate a sensor based on standard performance criteria and appropriateness for a given application.
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Prerequisites: (valid for students admitted to programmes within which the course is offered)
Biochemistry and Cell Biology, Materials for Biomedical Engineering
Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshhold requirements for progression within the programme, or corresponding.
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Organisation:
The course includes tutorial sessions, seminars, lectures, group works and laboratory work.
Laboratory work:
Laboratory tasks/demonstrations will be held at the IFM: students will be asked to prepare, for each demonstration/exercise, a report or to answer to a questionary.
Group work
Students will be divided in teams, and each team will be assigned a research article.
Each team will be asked to prepare a presentation (to be present in front of the class). Moreover each student will be asked to prepare a individual assay to demonstrate her/his understanding of the assigned article.
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Course contents:
- Introduction to biosensors,
- Biorecognition elements,
- Transduction principle,
- Surface functionalization in biosensors,
- Surface plasmon resonance biosensors (Biacore),
- Catalytic biosensors (glucosensor),
- Antibodies based biosensors,
- DNA based biosensors,
- Nanomaterial in biosensor technology,
- Microsystem working principles and their application to biosensor technology,
- Analytical parameters for sensor evaluation.
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Course literature:
Lecture notes, Scientific articles and suggested books:
Handbook of Biosensors and Biochips; Robert S. Marks, Christopher R. Lowe, David C. Cullen, Howard H. Weetall, Isao Karube, (2007) Wiley (available as e-book)
Chemical sensors and biosensors; Brian R. Eggins (2002) Wiley (available in the library)
Biosensors. The Practical Approach Series, Cooper, Jonathan M.; Cass, Anthony E. G. (2004), Volume 268 (available in library)
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Examination: |
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Written tests
Laboratory work and reports
Group work excercise
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2,5 ECTS
1 ECTS
2,5 ECTS
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Grading will be based on final written test, laboratory reports and group work exercise. When all assignments are approved a final grade will be calculated as a weighted mean where the written examination gives 60% of the final mark and the group work will contribute with 40%. |
Course language is English.
Department offering the course: IFM.
Director of Studies: Magnus Boman
Examiner: Edwin Jager
Link to the course homepage at the department
Course Syllabus in Swedish
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