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Linköping Institute of Technology

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Valid for year : 2011
 
NBID56 Adaptation, Genes and Molecular Evolution, 7,5 ECTS credits.
/Adaptation, gener och molekylär evolution/

For:   ETH   MOL  


OBS!

The course is scheduled fulltime during the first half of ht2. It should be combined with NBID44.

 

Prel. scheduled hours: 60
Rec. self-study hours: 140

  Area of Education: Science

Main field of studies: Biology, Chemical Biology

  Advancement level (G1, G2, A): A

Aim:
The student will increase her/his understanding of the concept of adaptation in a physiological and an evolutionary context. The student will increase her/his understanding on the genetic basis for evolution and phenotypic diversity.The student will analyze and discuss classical and modern examples of adaptation at two levels of organization: organismal and molecular.

Prerequisites: (valid for students admitted to programmes within which the course is offered)
Basic proficiency in the search in scientific databases, paper retrieval and basic rules in the citation of scientific information

Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshhold requirements for progression within the programme, or corresponding.

Supplementary courses:
Molecular Physiology

Organisation:
The course consists of lectures, seminars and a literature project. The students are expected to work independently and manage their time efficiently in order to handle the course assignments. Extra costs due to travelling and living must be paid by the student.

Course contents:
The course will both revise and refine the concept of adaptation with special emphasis on the modern criteria to distinguish between physiological and evolutionary adaptation and also give a grounding on the genetic basis for evolution and phenotypic diversity. Examples will be presented and common deviations from scientifically acceptable definitions will be discussed. Classical and current concepts in identifying the genetic basis for phenotypes and disease will be reviewed, from early linkage studies in Drosophila through to current whole genome association methods and resequencing projects. Sexual selection and its differences and similarities to natural selection, as well as the evolution of sex itself will also be discussed. The students will work on an essay discussing a specific case of evolutionary adaptation at the organismic or molecular level

Course literature:
As basic textbooks to cover the background of evolution and genetics, one of the following: Evolution. 2nd edition (2003). Mark Ridley. Oxford University Press. ISBN-10 â?" 0199267944. ISBN-13 â?" 978-0199267941. Evolutionary Analysis. 4th edition (2007). Scott Freeman and Jon C.Herron. Pearson Education. ISBN-10 â?" 0132397897. ISBN-13 â?" 978-0132397896.
As complementary books, the following are of relevance: Evolutionary pathways in nature. A phylogenetic approach(2006). John C.Avise. Cambridge University Press. ISBN-10 â?" 0521674174. ISBN-13 â?" 978-0521674171. Reading the story in DNA. A beginnerâ?Ts guide to molecular evolution (2008). Lindell Bromham. Oxford University Press. ISBN-10 â?" 0199290911. ISBN-13 â?" 978-0199290918.


Examination:
Written examination
Attendance and participation in seminars
Adaptation essay
2,5 ECTS
1,5 ECTS
3,5 ECTS
 
For the final grade in the course the different grades in the included parts are weighted taking into account their different sizes.



Course language is English.
Department offering the course: IFM.
Director of Studies: Agneta Johansson
Examiner: Dominic Wright
Link to the course homepage at the department


Course Syllabus in Swedish

Linköping Institute of Technology

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Contact: TFK , val@tfk.liu.se
Last updated: 11/01/2011