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Linköping Institute of Technology

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Valid for year : 2011
 
TBME08 Biomedical Modeling and Simulation, 6 ECTS credits.
/Biomedicinsk modellering och simulering/

For:   BME   Y  

 

Prel. scheduled hours: 50
Rec. self-study hours: 110

  Area of Education: Technology

Main field of studies: Biomedical Engineering

  Advancement level (G1, G2, A): A

Aim:
The objective of this course is to introduce the general theory of modeling and simulation of a variety of systems: physical processes, computer systems, biological systems and natural processes. After passing the course the student should be able to:
  • identify and describe the principles of discrete-event, continuous, and hybrid system modeling, and
  • use these principles to construct models of a number of realistic systems.
  • apply computational issues and analysis techniques associated with the modeling paradigms
  • develop simulation algorithms applicable to biomedical engineering problems
  • apply and implement computer-based modeling and simulation in medicine, including diagnostics, therapeutics, research and training.


Prerequisites: (valid for students admitted to programmes within which the course is offered)
Anatomy and physiology. Medical imaging. Prior object-orientation modeling experience is helpful, although not assumed. Programming maturity is assumed.

Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshhold requirements for progression within the programme, or corresponding.

Organisation:
The course has a student-centered focus with tutorial sessions, seminars, lectures, workshops and laboratory work as keystones.

Course contents:
Introduction to systems modeling concepts, modeling formalisms and their simulators, discrete and continuous event systems modeling, Hybrid systems and Stochastic systems. The use of diagnostic images to develop computer models and simulations that exhibit physical and physiological realism. Multi-level visualization and multi-scale modeling to connect the simulations and visualization of multiple levels of cells, tissues, and organs. Computational models of physiology embedded within computer graphics models and diagnostic image-based models of anatomy, to enable more realistic and accurate simulations. Models of cells and subcellular systems and cellular processes and the creation of a framework for post-genomic analysis. Study and derive end-user applications, with an emphasis on training medical personnel and the use of distributed visualization and simulation in medical education.

Course literature:
Modeling Biological Systems: Principles and Applications. Haefner J.W., 2005. Handbook of Dynamic System Modeling, Fishwick P.A.,2007.
Articles and www-material, IMT 2009.


Examination:
Written examination
Laboratory work
3 ECTS
3 ECTS
 



Course language is English.
Department offering the course: IMT.
Director of Studies: Göran Salerud
Examiner: Marcus Larsson
Link to the course homepage at the department


Course Syllabus in Swedish

Linköping Institute of Technology

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Contact: TFK , val@tfk.liu.se
Last updated: 04/29/2011