| NKED20 |
Pharmaceutical Development, 6 ECTS credits.
/Läkemedelsutveckling/
For:
KeBi
KOS
PRO
TB
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Prel. scheduled
hours: 48
Rec. self-study hours: 112
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Area of Education: Science
Main field of studies: Engineering Biology, Chemical biology
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Advancement level
(G1, G2, A): A
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Aim:
The course will provide knowledge about the different processes involved when going from discovery to approval of a pharmaceutical. After completing this course the student should be able to:
- understand the principles of the drug discovery and development process
- realize the principles of pharmaceutical mode of action and classification
- know major pharmaceutical groups and clinical uses in selected areas
- apply pharmacological methodology
- understand the basics of pharmacokinetics
- analyze various types of drugs specific conditions from production to use
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Prerequisites: (valid for students admitted to programmes within which the course is offered)
Three years of studies in the field of Chemistry or Biotechnology.
Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshhold requirements for progression within the programme, or corresponding.
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Organisation:
The course incudes lectures, seminars and laboratory work.
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Course contents:
Overview of the drug discovery and pharmaceutical development process
Pharmacodynamics: pharmaceutical molecular / cellular mechanisms of actions towards membrane proteins (receptors, ion channels) and intracellular proteins (transcription factors, enzymes), and various forms of receptor agonism and antagonism.
Pharmacokinetics: drug absorption, distribution and elimination. Laboratory workshop including computer simulations.
Drug development: pre-clinical/clinical phases and drug regulatory regulations.
Major drug groups, such as small molecules and biopharmaceuticals, and their clinical use in treating cancer, cardiovascular diseases, stroke and neurodegenerative diseases, as well as a presentation of chemotherapy, antibiotics and anti-inflammatory drugs.
Critical evaluation of scientific paper with focus on research methodology.
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Course literature:
Drug Discovery and Development -Technology in Transition, Raymond G. Hill and Humphrey B. Rang, 2nd edition, 2012, and scientific articles.
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Examination: |
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Written examination
Group assignments including written and oral presentations (U,G)
Laboratory work
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4 ECTS
1,5 ECTS
0,5 ECTS
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Course language is English.
Department offering the course: IFM.
Director of Studies: Magdalena Svensson
Examiner: Peter Nilsson
Course Syllabus in Swedish
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