| TFKE18 | Biological Measurements, 7,5 ECTS credits. /Biomätteknik/ |
||
Prel. scheduled
hours: 60 |
|||
|
Area of Education: Science Subject area: Chemistry |
|||
| Advancement level
(A-D): C
|
|||
| Aim: After taking this course, the student should have good knowledge about the principles behind a range of biophysical, analytical and biological measurement techniques currently used to solve biological problems within biomedical research and industry. The aim is that the student should learn to understand, use and suggest optimal methods for the study of specific biological or biochemical issues of investigation. The course is primarily directed towards biomolecular studies. |
|||
| Prerequisites: (valid for students admitted to programmes within which the course is offered) NKEC52 Biokemi 2 (or similar). Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshhold requirements for progression within the programme, or corresponding. |
|||
| Organisation: Lectures, seminars and laboratory exercises. |
|||
| Course contents: Different optical methods for the study of biological systems, such as UV, IR, FT-IR, circular dichroism (CD) and fluorescence spectroscopy, calorimetric methods, surface plasmon resonance (SPR), and the fundamental principles for separation by macromolecular mobility in centrifugal and electrical fields, such as electrophoresis, sedimentation analysis and mass spectrometry. In a literature project, the students will apply their knowledge by proposing the use of biomeasurement technologies in an analysis of a real biological or biochemical problem. The laboratory exercises will include practice or demonstration of a majority of the techniques treated in the lecture course. |
|||
| Course literature: Compendium with extracts from reference literature, reviews, scientific articles and laboratory handouts. The reference literature includes: Biophysical Chemistry part II. Cantor & Schimmel, Freeman NY 1980. Principles of Physical Biochemistry. VanHolde, Johnsson & Ho. Prentice Hall 1998. Principles and techniques of practical biochemistry. Wilson & Walker, Cambridge University Press 2000. Protein-Ligand Interactions: hydrodynamics and calorimetry samt Protein-Ligand Interactions: structure and spectroscopy, Harding & Chowdry, Oxford University Press 2001. |
|||
| Examination: | |||
| A written examination A laboratory course including literature projekt |
3 p 2 p |
||
Course language is Swedish. Department offering the course: IFM. Director of Studies: Stefan Svensson Examiner: Maria Sunnerhagen Course Syllabus in Swedish |
|||
|
|
 |
|||||
| ||||||