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COURSE TITLE

Pharmacodynamics, 7,5 points

COURSE CATEGORY   Programkurs/Fristående kurs MAIN FIELD OF STUDY   SUBJECT AREA     COURSE CODE   OMBPHA

AIM OF THE COURSE

This course aims to provide an advanced understanding of the mechanisms of drug action and the relation between drug concentration and effect. Furthermore, the course will focus both on recent resarch within some field of pharmacology and on modern techniques available to study and elucidated the molecular and cellular basis of how drugs act.

CONTENTS

* Overview of pharmacokinetics (drug absorption, distribution and elimination) and therapeutics. * Drugs that interact with transmembrane proteins (e.g. receptorproteins, ion-channels, cell adhesion molecules, carriers and enzymes). * Drugs that interfere with intracellular target proteins (e.g. enzymes, steroidreceptors and cytoskeletal proteins) and with replication, transcription and translation. * Current concept of drug/receptorprotein interaction. * Drugs that affect the neuron and neurotransmission including cholinergic, adrenergic and peptidnergic transmission. * Drugs that affect muscle cells. * Drugs that affect inflammatory cells. * Principles of gene- and immunotheraphy.

TEACHING

Lectures, turorial groups, seminars, practical och computer-based laborations. The educational method used is problem-based learning (PBL). PBL emphasises the student´s development of free, self-supporting, lifelong learning ability as an instrument for critical inquiry. The students own queries and formulated problems form the basis of PBL. Important is also the student´s ability to take responsibility for his/her own learning, and to seek and evaluate information and knowledge and to train co-operation and flexible attitude to different views and ideas.

EXAMINATION

Active participation in tutorial groups and seminars. Written examination. Students, which have not passed on the regular examination occasion, are normally offered four additional opportunities according to this syllabus, one of which is close in time to the first examination occasion. Students who have failed three times on the course or part of the course are entitled to request another examiner at the new examination occasion.

ADMISSION REQUIREMENTS

Bachelor of Science in Biomedicine or other related subjects such as Medicine or Biology. At least three years of full-time undergraduate studies in a relevant main subject. For students in the Medical Biology Programme, 160 credits: Passed semester 1 to 5. Obs! To be admitted to courses taught in English you must fulfil the requirement of at least one year of full-time undergraduate studies. Documented knowledge of English equivalent to "Engelska B" is required, or an international proficiency test, e.g. TOEFL, minimum score 550/213.

GRADING

CERTIFICATE

COURSE LITERATURE

The course literature is decided upon by the department in question.

OTHER INFORMATION

Pharmacodynamics Pharmacodynamics   Department responsible for the course or equivalent: MEDBIO - Medicinsk biologi             Registrar No:   Course Code: OMBPHA           Exam codes: see Local Computer System       Subject/Subject Area :                       Level   Education level     Subject Area Code   Field of Education   D         Medicin