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COURSE TITLE

Infection Biology - Clinical Perspectives, 7,5 credits, 7,5 points

COURSE CATEGORY   Single subject course MAIN FIELD OF STUDY   Medical Biology SUBJECT AREA   Medical Biology   COURSE CODE   8FA223

AIM OF THE COURSE

In this course the students will obtain advanced knowledge of infectious medicine, medical microbiology, and virology within the fields of chronic infections, biomaterials, global medicine, and perinatal infections. LEARNING OUTCOMES By the end of the course the students will be able to: Knowledge and understanding - Describe the mode of action of different microorganisms pathogenic to humans - Define the interactions between the human host and the infectious agent, from molecular to clinical level and apply this knowledge to describe clinical manifestations - Apply the principles of mode of actions of virulence factors on the defence of the human body Competence and skills - Design and carry out laboratory experiments to investigate molecular mechanisms in the interactions between microorganisms and human cells Judgement and approach - Understand, analyze and critically discuss scientific papers in the field of infection biology

CONTENTS

- Microorganisms infecting the human body - The host response to infectious micro organisms - Virulence strategies and mechanisms exerted by the pathogenic micro organism - The ecology of human flora of microorganisms - normal flora and pathogens - Microorganisms and the immune system - Vaccines and vaccine development - Antimicrobial agents and resistance to them - Epidemiology of human infectious diseases - Zoonosis - Infectious diseases in the perspective of global medicine - Emerging infectious diseases - Infections and human genetics

TEACHING

General: Linköping University Master’s Programme in Experimental and Medical Biosciences applies student-centered learning among which Problem Based Learning (PBL) is one pedagogical philosophy and method. To prepare the students for future employment, practical and experimental work in laboratory settings are important parts of the programme in courses as well as in individual projects. Specific: In this course lectures, tutorial groups, seminars, study visits, demonstrations and laboratory work are used.

EXAMINATION

COMPULSORY ITEMS Active participation in the compulsory parts is necessary to pass the course, and assessment of them is carried out continuously. Compulsory parts in this course are: tutorial groups, laboratory work, and demonstrations. EXAMINATION Individual written examination. Literature assignment including a written report and oral presentation of an in-depth study (group assignment with individual assessment). SCOPE OF RE-EXAMINATION The extent of a re−examination shall be similar to the regular examination. CHANGE OF EXAMINERS Students who have failed the course or part of the course twice are entitled to request another examiner for the following examination occasion, unless specific reasons are present. REGISTRATION FOR EXAMINATION The procedure for registration should be stated prior to the commencement of each course. In other respects, regulations concerning examination and examiners are applied in accordance with Linköping University policy.

ADMISSION REQUIREMENTS

At least three years of full-time undergraduate studies (180 credits) in a major subject area with relevance for biomedical sciences. This could include previous studies at faculties of medicine, technology/natural sciences, odontology or veterinary medicine. A major part of courses (90 credits) should be in subjects such as biochemistry, cell biology, molecular biology, genetics, gene technology, microbiology, immunology, histology, anatomy, and pathology. The lowest acceptable grade from undergraduate studies is Pass. Applicants must also have documented knowledge of English equivalent to Engelska B/Engelska 6; i.e. an internationally recognized test, e.g. TOEFL (minimum scores: Paper based 575 + TWE-score 4.5, and internet-based: Score of 20 (scale 0-30) in written test, total score of 90), IELTS, academic (minimum score: Overall mark of 6.5 and no section below 5.5), or equivalent.

GRADING

The course is graded on the following scale: Pass; Fail.

CERTIFICATE

Course certificates are issued by the Board of the Faculty of Health Sciences when requested by the student.

COURSE LITERATURE

The course literature is decided upon by the department in question.

OTHER INFORMATION

The planning and implementation of a course must take its starting point in the wording of the course plan. The course evaluation included in each course must therefore take up the question how well the course agrees will the course plan. The course is carried out in such a way that both men’s and women’s experience and knowledge is made visible and developed. If the course is withdrawn, or is subject to major changes, examinations according to this course plan are normally offered on a total of three occasions within one year, one of them in close connection to the first examination.

Infection Biology - Clinical Perspectives, 7,5 credits Infektionsbiologi med kliniska perspektiv   Department responsible for the course or equivalent: IKE- Institutionen för Klinisk och Experimentell medicin             Registrar No:   Course Code: 8FA223           Exam codes: see Local Computer System       Subject/Subject Area : Medical Biology                       Level   Education level     Subject Area Code   Field of Education         MB1   Medicine