Kursplan

COURSE TITLE

Tumour Biology, 7,5 points

COURSE CATEGORY   Fristående kurs
MAIN FIELD OF STUDY
SUBJECT AREA

COURSE CODE

8FA025

AIM OF THE COURSE

The purpose of the course is for the student to obtain advanced knowledge about tumour development in general including the genetic basis of human cancer. Furthermore, the course will give an overview of cancer by site taking into account different clinical and biological aspects as well as the occurrence of specific gene alterations. The course comprises in-depth knowledge in medical biology.

By the end of the course the students will be able to:
-Discuss specific capabilities of cancer cells and how they are related to genetic alterations and normal cell biology and development
-Integrate knowledge in cancer biology in order to discuss different human malignancies in relation to age, sex, hormonal influence, environmental factors, as well as molecular alterations
-Design an experiment in order to analyse how alterations in cell signalling may interfere with the cellular response to damage
-Integrate the results of a series of experiments and make conclusions by applying knowledge in cancer biology
-Apply knowledge in cancer biology in order to discuss new hypotheses in the field of cancer research, such as cancer stem cells
-Identify the state of the art of a chosen topic by a literature search and summarise the findings in an oral presentation and a written abstract

CONTENTS

-Concepts in cancer genetics
-Control of the cell cycle and cancer
-Caretaker genes
-Apoptosis and cancer
-Immortalization
-Tumour progression
-Mechanisms of invasion and metastatis
-Angiogenesis and cancer
-Tumour immunology
-Hormones and cancer
-Cancer by the site: different spectra of malignancies in relation to age, sex, hormones, and molecular biology

TEACHING

Lectures, tutorial groups, seminars and laboratory work. The educational method used is problem-based learning (PBL), PBL emphasises the student´s development of free, self-supporting, lifelong learning ability as an instrument for critical inquiry. The students own queries and formulated problems form the basis of PBL. Important is also the student´s ability to take responsibility for his/her own learning, and to seek and evaluate information and knowledge and to train co-operation and a flexible attitude to different views and ideas.

Two main laboratory works are included in the course. Each of them consists of different parts. The design is in part decided by the tutorial group. The results of the first laboratory works will be discussed in the tutorial group and presented at a seminar. The second laboratory works will be summarised in a written report on an individual basis.

During the course each participant should choose one topic for a study in-depth. The studies will be presented at a final seminar.

The results of the first laboratory works and the results of deeper studies will be presented and discussed at seminars. The participation is compulsory.

EXAMINATION

Examination forms include active participation in tutorial groups and seminars, written and oral examinations, completed assignments and examination of practical skills.

Students who have failed two times on the course or part of the course are entitled to request another examiner at the new examination occasion.

Extent of re-examination:
The extent of a re-examination shall be similar to the regular examination.

Entries for examinations:
Rules for entries for examination are given in the course plan. Besides are "Regulations regarding examinations and examinators" according to decision Linköpings University Dnr: LiU 1109/00-40 applied.

ADMISSION REQUIREMENTS

Regulations concerning general eligibility in accordance with the Higher Education Ordinance, Section 7, paragraph 28 and in addition special requirements in accordance with Section 7, paragraph 31, i.e. at least three years of full-time undergraduate studies in a main subject area with relevance for Life Science, e.g. from faculties within medicine, technical/natural sciences, odontology, pharmaceutical science. The lowest acceptable grade from undergraduate studies is Pass.

Applicants with a degree from a non-Swedish university must enclose an official examination certificate for at least three years of fulltime studies in subjects with relevance for Life Science, such as biology, chemistry, medicine or corresponding. If English is not the mother tongue of the applicant, he or she must also be able to prove proficiency in English. This may be done by submitting results from an internationally recognised test e.g. the TOEFL-test or prove that the education at basic level has been performed in English. Applications must be supported by official documents issued by a recognised university or other authority.

GRADING

The course is graded on the following scale: Pass; Fail.

CERTIFICATE

Course certificate is issued by the Faculty Board on request. The Department provides a special form which should be submitted to the Student Affairs Office at the Faculty of Health Sciences.

COURSE LITERATURE

The course literature is decided upon by the department in question.

OTHER INFORMATION

Pass or Fail.

Planning and implementation of the course shall be carried out from the wording in this course plan. The evaluation of the course should therefore consider the question how well the course agrees with the course plan. The evaluation will be written on a scheduled time point at the end of the course.
Electronic evaluation of the course in accordance with Linköping University´s regulations will in addition be done (Dnr LiU 780/06-04).

At the student´s request, course certificate is issued by the director of studies for courses or, according to delegation, by the head of the department/director of programme studies.

The course organiser at the Department of Biomedicine and Surgery will provide a list of relevant literature at the latest two months before the start of the course.

The course is given in such a way that both men´s and women´s experiences and knowledge are made visible and developed.

If the course is closed down, or is subject for major changes, is normally examination according to this course plan offered on totally three occasions within a year, of which one in close connection to the first examination.

Tumour Biology
Tumour Biology, advanced course

Department responsible
for the course or equivalent: MEDBIO - Medicinsk biologi

Registrar No: LiU 1410/06-41

Course Code: 8FA025

Exam codes: see Local Computer System

Subject/Subject Area :

Level		Education level			Subject Area Code		Field of Education
Avancerad					MBI		Medicin

2007-02-15